Courtesy of Justin Fore at Fore Innovations LLC:
E-85 is relatively challenging fuel to properly implement on a modified, high performance vehicle due to it's low specific energy and corrosive nature. The low specific energy mean that you need MORE fuel to produce the same power with gasoline. The corrosive nature has been found to not be a great concern on high performance automobiles at this point; however, it is important to ensure that your injectors and filters are adequate for E-85 and the entire fuel system undergoes a thorough inspection every 3-6 months.